OCT (left) and IVUS (right) are simultaneously used to acquire real-time images of a blood vessel. A probe attached to a guide wire rotates about the longitudinal axis with respect to the vessel. During rotation, the probe emits infrared light and ultrasonic waves to the nearby tissue. The light and sound waves collected back from the tissue into the probe are transferred up through the guide wire where raw OCT and IVUS images are produced by a computer.OCT provides image resolutions of 1-15um with approximately 2-3mm imaging depth while IVUS provides image resolutions of around 100um with approximately 4-8mm imaging depth. As a result, both high-resolution and relatively deep image penetration of tissues is achieved.
The ability to provide real-time imaging inside coronary vessels has many implications on the quality of diagnosis and treatment of cardiovascular diseases. OCT combined with IVUS enables micrometer resolution image quality and deeper image penetration depth that has the potential to assess plaque formation and location inside coronary vessels. OCT Medical Imaging has developed a modular component that can easily be integrated with catheter and endoscopic-based technologies in the body in order to see more with light and sound.
Current disposable intravascular OCT or intravascular IVUS probes are sold separately. By combining these two technologies together into a single disposable probe, OCTMI:
- Reduces cost of disposables
- Provides physician ability to sequential or multi-modal imaging
- Improves multi-modal imaging accuracy
- Eliminates need to interchange catheters
- Reduces procedure time
- Increases productivity and likely improves outcome and comforts patients
OCTMI's IP platform embodies technologies that provide high-resolution structural and functional images of living tissues across specialties and solves major issues in early detection and diagnosis of cancer and cardiovascular diseases. High-resolution 3D cross-sectional images obtained using OCTMI technology detect objects one hundredth of the size of a pin-head such as normal, benign, and malignant structures at and below tissue surface, generally undetectable by imaging modalities such as MRI and CT. OCTMI technology replaces traditional low resolution technologies with a minimally invasive real-time 3D imaging technique that is efficient, cost-effective, and is an easily adaptable complement with existing imaging technologies.